Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
crygm7Crystallin, gamma M7; Belongs to the beta/gamma-crystallin family. (174 aa)    
Predicted Functional Partners:
tas1r1
Taste receptor, type 1, member 1.
      
 0.754
cryaba
Crystallin, alpha B, a; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.596
mpv17
Protein Mpv17; Involved in mitochondrial homeostasis, and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance. Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress (By similarity). Belongs to the peroxisomal membrane protein PXMP2/4 family.
   
  
 0.506
edar
Ectodysplasin A receptor.
      
 0.503
crybb2
Crystallin, beta B2; Belongs to the beta/gamma-crystallin family.
   
 
0.454
cryaa
Crystallin, alpha A; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.452
ush2a
Usher syndrome 2A (autosomal recessive, mild).
      
 0.444
zgc:112437
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
  
     0.433
skp1
S-phase kinase-associated protein 1A; Belongs to the SKP1 family.
      
 0.432
cldne
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
  
     0.424
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.