Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ncf4Neutrophil cytosolic factor 4. (355 aa)    
Predicted Functional Partners:
cyba
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
   
 0.999
ncf1
Neutrophil cytosolic factor 1.
   
0.999
ncf2
Neutrophil cytosolic factor 2.
   
0.998
cybb
Cytochrome b-245, beta polypeptide (chronic granulomatous disease).
   
 0.997
noxa1
NADPH oxidase activator 1.
   
 0.996
nox5
NADPH oxidase, EF-hand calcium-binding domain 5.
   
 0.991
Nox4
NADPH oxidase 4.
   
 0.991
duox
Dual oxidase.
   
 0.990
rac2
Rac family small GTPase 2.
   
 0.966
nox1
NADPH oxidase 1.
   
 0.946
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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