STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tskuTsukushin; Dorsalizing factor. Functions as an inhibitor of bone morphogenetic proteins (BMP) during gastrulation. (347 aa)    
Predicted Functional Partners:
tlr8a
Toll-like receptor 8a; Belongs to the Toll-like receptor family.
    
 
0.800
tbrg1
Transforming growth factor beta regulator 1.
      
 0.761
unc93b1
Unc-93 homolog B1, TLR-signaling regulator.
    
  0.722
isy1
ISY1-splicing factor homolog.
    
 
 0.666
hspa13
Heat shock protein 70 family, member 13.
    
 
 0.644
acer3
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
      
 0.635
stoml1
Stomatin (EPB72)-like 1.
   
  
 0.587
gk5
Putative glycerol kinase 5; Belongs to the FGGY kinase family.
   
 
 0.583
chrd
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity); Belongs to the chordin family.
   
 
 0.567
cth1
Putative zinc finger protein.
    
 
 0.567
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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