Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tcf25Transcription factor 25 (basic helix-loop-helix). (650 aa)    
Predicted Functional Partners:
LTN1
Si:dkey-175g6.5.
   
 0.991
LOC108182745
NFACT-R_1 domain-containing protein.
   
 
 0.953
def8
Differentially-expressed in FDCP 8 homolog.
 
 
  
 0.926
rpl30
Ribosomal protein L30.
    
  0.871
rpl6
Ribosomal protein L6.
    
 0.860
rpl13a
Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.
    
  0.858
rpl32
Ribosomal protein L32.
    
  0.857
rpl10
60S ribosomal protein L10; Component of the large ribosomal subunit (Probable). Plays a role in the formation of actively translating ribosomes. Plays a role in the embryonic brain development.
    
  0.857
rpl35a
Ribosomal protein L35a.
    
  0.856
rpl23a
Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family.
    
  0.855
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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