Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lgals9l3Galectin. (320 aa)    
Predicted Functional Partners:
rsad2
Radical S-adenosyl methionine domain-containing protein 2; Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon; Belongs to the radical SAM superfamily. RSAD2 family.
   
 
 0.830
havcr2
Hepatitis A virus cellular receptor 2.
    
 
 0.793
slc38a9
Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...]
    
 
 0.733
pbk
Lymphokine-activated killer T-cell-originated protein kinase homolog.
    
   0.727
lgals3bpb
Galectin-3-binding protein B; Promotes integrin-mediated cell adhesion.
   
 
 0.666
lgals3a
Galectin.
    
 
0.649
usp18
Ubiquitin-specific peptidase 18; Belongs to the peptidase C19 family.
   
 
 0.647
lgals3b
Galectin.
    
 
0.630
lgals3bpa
Galectin-3-binding protein A; Promotes integrin-mediated cell adhesion.
   
 
 0.623
cmklr1l1
Chemokine-like receptor 1 like 2; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.603
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.