Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mier1aMesoderm induction early response 1a, transcriptional regulator. (469 aa)    
Predicted Functional Partners:
tcf25
Transcription factor 25 (basic helix-loop-helix).
      
 0.773
ubtf
Upstream-binding transcription factor.
    
 
 0.723
ube2ia
SUMO-conjugating enzyme UBC9-B; Accepts the ubiquitin-like proteins sumo1, sumo2 and sumo3 from the uble1a-uble1b E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as ranbp2 or cbx4. Essential for nuclear architecture and chromosome segregation (By similarity). Mediates nuclear localization of vsx1. Required for progression through mitosis during organogenesis. Belongs to the ubiquitin-conjugating enzyme family.
      
 0.682
bahd1
Bromo adjacent homology domain-containing 1.
    
 
 0.680
LOC100331694
BAH domain-containing protein.
    
 
 0.680
lrrfip1a
Leucine-rich repeat (in FLII)-interacting protein 1a.
   
  
 0.675
C7H16orf87
UPF0547 protein C16orf87 homolog; Belongs to the UPF0547 family.
    
   0.652
dmap1
DNA methyltransferase 1-associated protein 1.
    
   0.650
mrgbp
C20orf20 homolog (H. sapiens).
    
   0.644
cdyl
Chromodomain protein, Y-like.
    
 
 0.629
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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