Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
chkaCholine kinase alpha. (418 aa)    
Predicted Functional Partners:
chkb
Choline kinase beta.
  
 
0.989
pcyt1ba
Phosphate cytidylyltransferase 1, choline, beta a.
   
 
 0.980
pcyt2
Phosphate cytidylyltransferase 2, ethanolamine.
   
 
 0.968
pcyt1aa
Phosphate cytidylyltransferase 1, choline, alpha a.
   
 
 0.963
pcyt1bb
Phosphate cytidylyltransferase 1, choline, beta b.
   
 
 0.963
gpcpd1
Glycerophosphocholine phosphodiesterase 1.
    
 0.958
pmt
Phosphoethanolamine methyltransferase.
    
 0.956
etnppl
Ethanolamine-phosphate phospho-lyase; Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde.
     
 0.955
chata
Choline O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. Belongs to the carnitine/choline acetyltransferase family.
   
 
 0.952
phospho1
Probable phosphatase phospho1; Probable phosphatase, involved in bone mineralization. Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.
     
 0.946
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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