Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
thap3THAP domain-containing, apoptosis-associated protein 3. (213 aa)    
Predicted Functional Partners:
thap4
THAP domain-containing 4.
      
 0.994
dnajc11a
DnaJ (Hsp40) homolog, subfamily C, member 11a.
   
  
 0.895
dnajc11
DnaJ (Hsp40) homolog, subfamily C, member 11b.
      
 0.839
LOC100537455
Uncharacterized protein.
      
 0.708
gtf2h4
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
   0.647
klhdc10
Kelch domain-containing 10.
      
 0.646
si:dkey-6b12.5
Si:dkey-6b12.5.
      
 0.638
klhl21
Kelch-like protein 21; Substrate-specific adapter of BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB (By similarity).
      
 0.618
blzf1
Basic leucine zipper nuclear factor 1.
      
 0.612
asb6
Ankyrin repeat and SOCS box-containing 6.
      
 0.604
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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