STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wdr18WD repeat-containing protein 18; Involved in left-right determination through controlling the correct clustering and migration of dorsal forerunner cells (DFCs) and Kupffer's vesicle formation. Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity) (431 aa)    
Predicted Functional Partners:
tex10
Testis-expressed protein 10 homolog; Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit
   
 0.999
wdr12
Ribosome biogenesis protein wdr12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome
  
 
 0.996
nol9
Nucleolar protein 9
   
 0.995
pes
Pescadillo; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome
   
 
 0.994
LOC561321
LAS1-like, ribosome biogenesis factor; LAS1-like (S. cerevisiae)
   
 0.994
gnl2
Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation
   
 
 0.989
PELP1
Proline, glutamate and leucine rich protein 1
   
 0.988
gnl3
Guanine nucleotide-binding protein-like 3; May play a role in regulating cellular proliferation
   
 0.987
ebna1bp2
EBNA1 binding protein 2
   
 
 0.984
senp3b
SUMO1/sentrin/SMT3-specific peptidase 3b; Eukaryotic translation initiation factor 4A, isoform 1A
   
 0.983
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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