STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
blmhBleomycin hydrolase; Belongs to the peptidase C1 family. (453 aa)    
Predicted Functional Partners:
sh3bgrl
SH3 domain-binding glutamic acid-rich-like protein; Belongs to the SH3BGR family.
      
 0.816
lyrm4-2
Si:ch211-152c8.4; Belongs to the complex I LYR family.
      
 0.803
nudt12
Nudix (nucleoside diphosphate-linked moiety X)-type motif 12.
   
 
 0.748
wdr73
WD repeat-containing protein 73; May play a role in the regulation of microtubule organization and dynamics; Belongs to the WD repeat WDR73 family.
   
  
 0.744
dnajb12a
DnaJ heat shock protein family (Hsp40) member B12a.
   
  
 0.744
znf207b
Zinc finger protein 207, b.
   
  
 0.736
crlf3
Cytokine receptor-like factor 3; May play a role in the negative regulation of cell cycle progression; Belongs to the cytokine receptor-like factor 3 family.
      
 0.718
morf4l1
Mortality factor 4-like 1.
      
 0.717
ttc19
Tetratricopeptide repeat protein 19, mitochondrial; Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1. Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation into the complex III and whose presence is detrimental for its catalytic activity.
      
 0.692
usp37
Ubiquitin carboxyl-terminal hydrolase 37; Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of APC/C target proteins, thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex (By similarity); Belongs to the peptidase C19 family.
      
 0.681
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.