Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
blmhBleomycin hydrolase; Belongs to the peptidase C1 family. (453 aa)    
Predicted Functional Partners:
nudt12
Nudix (nucleoside diphosphate-linked moiety X)-type motif 12.
    
 
 0.938
kera
Keratocan; May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
   
   0.937
sh3bgrl
SH3 domain-binding glutamic acid-rich-like protein; Belongs to the SH3BGR family.
      
 0.799
lmbrd1
Probable lysosomal cobalamin transporter; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity); Belongs to the LIMR family. LMBRD1 subfamily.
      
 0.720
spata4
Spermatogenesis-associated 4.
      
 0.706
bphl
Biphenyl hydrolase like.
      
 0.700
slc1a7a
Amino acid transporter.
      
 0.676
slc1a9
Amino acid transporter.
      
 0.676
slc1a2a
Amino acid transporter.
      
 0.676
aacs
Acetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.673
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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