Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ighmbp2Immunoglobulin mu DNA-binding protein 2. (997 aa)    
Predicted Functional Partners:
nelfe
Negative elongation factor complex member E.
    
 
 0.952
nelfa
Negative elongation factor complex member A.
   
   0.929
kansl3
KAT8 regulatory NSL complex subunit 3; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
      
 0.785
grsf1
G-rich RNA sequence-binding factor 1.
    
   0.780
mapk15
Mitogen-activated protein kinase.
      
 0.769
lrsam1
Leucine-rich repeat and sterile alpha motif-containing 1.
   
  
 0.744
abt1
Activator of basal transcription 1.
    
 
 0.730
uqcc3
Ubiquinol-cytochrome-c reductase complex assembly factor 3; Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.
      
 0.727
zc4h2
Zinc finger C4H2 domain-containing protein; Plays a role in GABAergic and V2 interneurons differentiation. Involved in motoneuron development and in neuromuscular junction formation.
      
 0.721
las1l
LAS1-like ribosome biogenesis factor.
   
  
 0.710
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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