Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
paqr5aMembrane progestin receptor gamma-A; Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation (By similarity); Belongs to the ADIPOR family. (345 aa)    
Predicted Functional Partners:
appl1
HESX homeobox 1.
    
 0.947
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper-containing 2.
    
  0.930
PAQR9
Progestin and adipoQ receptor family member 9.
     
0.879
pcolceb
Similar to procollagen C-endopeptidase enhancer.
      
 0.800
zpcx
Zona pellucida protein C.
      
 0.759
paqr8
Progestin and adipoQ receptor family member VIII.
     
0.758
paqr7b
Membrane progestin receptor alpha-B; Steroid membrane receptor. Signals upon progestin binding, resulting in rapid activation of MAPK and down-regulation of adenylyl cyclase activity. Interacts with steroids with varying degrees of affinity, showing specificity for activation by the maturation-inducing steroid (MIS) 4-pregnen-17,20beta-diol-3-one (17,20beta-DHP). Capable of mediating progestin-induced oocyte maturation.
  
  
0.755
pgrmc1
Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family.
   
 
 0.744
slc52a2
Solute carrier family 52 member 2.
      
 0.736
pgrmc2
Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family.
   
 
 0.720
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.