STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aagabAlpha and gamma adaptin-binding protein. (321 aa)    
Predicted Functional Partners:
ap1s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 
 0.885
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 
 0.857
mfsd9
Major facilitator superfamily domain-containing 9.
      
 0.608
pgap3
Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.
      
 0.608
exoc5
Exocyst complex component 5.
   
  
 0.575
tgfbrap1
Transforming growth factor-beta receptor-associated protein 1 homolog; Plays a role in the TGF-beta signaling pathway. Belongs to the TRAP1 family.
   
  
 0.563
m6pr
Mannose-6-phosphate receptor (cation-dependent).
   
  
 0.556
vti1b
Vesicle transport through interaction with t-SNAREs homolog 1B (Yeast).
   
  
 0.525
ccdc32
Coiled-coil domain-containing 32.
    
   0.518
ap2a1
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
   
   0.512
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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