Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dennd5aDENN/MADD domain-containing 5A. (1288 aa)    
Predicted Functional Partners:
rph3aa
Rabphilin 3A homolog (mouse), a.
   
  
 0.729
rph3ab
Rabphilin 3A homolog (mouse), b.
      
 0.719
avl9
AVL9 homolog (S. cerevisiase).
      
 0.670
slc35d1a
Solute carrier family 35 member D1a.
 
      0.636
plat
Plasminogen activator; Belongs to the peptidase S1 family.
   
  
 0.631
dennd3a
DENN/MADD domain-containing 3a.
    
 
 0.618
dennd4b
DENN/MADD domain-containing 4B.
    
 
0.602
rab24
RAB24, member RAS oncogene family.
      
 0.594
dennd4a
DENN/MADD domain-containing 4A.
    
 
0.578
itfg1
Integrin alpha FG-GAP repeat-containing 1.
      
 0.578
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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