STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nudt188-oxo-dGDP phosphatase NUDT18; Mediates the hydrolysis of oxidized nucleoside diphosphate derivatives. Hydrolyzes 8-oxo-7,8-dihydroguanine (8-oxo-Gua)-containing deoxyribo- and ribonucleoside diphosphates to the monophosphates. Hydrolyzes 8-oxo-dGDP and 8-oxo-GDP with the same efficiencies. Hydrolyzes also 8-OH-dADP and 2-OH-dADP. Probably removes oxidized guanine nucleotides from both the DNA and RNA precursor pools (By similarity). (325 aa)    
Predicted Functional Partners:
nudt5
Nudix (nucleoside diphosphate-linked moiety X)-type motif 5; Belongs to the Nudix hydrolase family.
      
 0.995
nudt15
Nudix (nucleoside diphosphate-linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family.
      
 0.985
nudt14
Nudix (nucleoside diphosphate-linked moiety X)-type motif 14.
      
 0.981
nudt17
Nucleoside diphosphate-linked moiety X motif 17; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family.
      
 0.974
nudt2
Nudix (nucleoside diphosphate-linked moiety X)-type motif 2.
      
 0.936
nudt12
Nudix (nucleoside diphosphate-linked moiety X)-type motif 12.
   
  
 0.901
nudt22
Nudix (nucleoside diphosphate-linked moiety X)-type motif 22.
      
 0.874
nudt1
Nudix (nucleoside diphosphate-linked moiety X)-type motif 1; Belongs to the Nudix hydrolase family.
      
 0.868
nudt9
Nudix (nucleoside diphosphate-linked moiety X)-type motif 9.
      
 0.868
nudt4a
Nudix (nucleoside diphosphate-linked moiety X)-type motif 4a.
   
  
 0.842
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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