| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gpatch1 | wdr83 | ENSDARP00000014631 | ENSDARP00000060977 | G patch domain-containing 1. | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. | 0.920 |
| gtf3aa | wdr83 | ENSDARP00000049330 | ENSDARP00000060977 | General transcription factor IIIAa. | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. | 0.749 |
| gtf3aa | wdr83os | ENSDARP00000049330 | ENSDARP00000119631 | General transcription factor IIIAa. | WD repeat domain 83 opposite strand. | 0.833 |
| gtf3ab | wdr83 | ENSDARP00000096703 | ENSDARP00000060977 | General transcription factor IIIA, b. | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. | 0.718 |
| gtf3ab | wdr83os | ENSDARP00000096703 | ENSDARP00000119631 | General transcription factor IIIA, b. | WD repeat domain 83 opposite strand. | 0.807 |
| hivep3a | wdr83 | ENSDARP00000115671 | ENSDARP00000060977 | HIVEP zinc finger 3a. | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. | 0.747 |
| lamtor2 | lamtor3 | ENSDARP00000058324 | ENSDARP00000116826 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | 0.999 |
| lamtor2 | wdr83 | ENSDARP00000058324 | ENSDARP00000060977 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. | 0.801 |
| lamtor3 | lamtor2 | ENSDARP00000116826 | ENSDARP00000058324 | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | 0.999 |
| lamtor3 | wdr83 | ENSDARP00000116826 | ENSDARP00000060977 | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. | 0.878 |
| luc7l | sf3b4 | ENSDARP00000072775 | ENSDARP00000022759 | LUC7-like (S. cerevisiae). | Splicing factor 3b, subunit 4. | 0.708 |
| luc7l | wdr83 | ENSDARP00000072775 | ENSDARP00000060977 | LUC7-like (S. cerevisiae). | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. | 0.824 |
| prpf8 | sf3b4 | ENSDARP00000121091 | ENSDARP00000022759 | Pre-mRNA-processing factor 8. | Splicing factor 3b, subunit 4. | 0.994 |
| prpf8 | wdr83 | ENSDARP00000121091 | ENSDARP00000060977 | Pre-mRNA-processing factor 8. | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. | 0.922 |
| sf3b4 | luc7l | ENSDARP00000022759 | ENSDARP00000072775 | Splicing factor 3b, subunit 4. | LUC7-like (S. cerevisiae). | 0.708 |
| sf3b4 | prpf8 | ENSDARP00000022759 | ENSDARP00000121091 | Splicing factor 3b, subunit 4. | Pre-mRNA-processing factor 8. | 0.994 |
| sf3b4 | wdr83 | ENSDARP00000022759 | ENSDARP00000060977 | Splicing factor 3b, subunit 4. | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. | 0.954 |
| wdr83 | gpatch1 | ENSDARP00000060977 | ENSDARP00000014631 | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. | G patch domain-containing 1. | 0.920 |
| wdr83 | gtf3aa | ENSDARP00000060977 | ENSDARP00000049330 | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. | General transcription factor IIIAa. | 0.749 |
| wdr83 | gtf3ab | ENSDARP00000060977 | ENSDARP00000096703 | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. | General transcription factor IIIA, b. | 0.718 |