Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mt2Metallothionein-2; Metallothioneins have a high content of cysteine residues that bind various heavy metals; Belongs to the metallothionein superfamily. Type 1 family. (60 aa)    
Predicted Functional Partners:
mtbl
Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.
      
 0.683
slc30a1a
Solute carrier family 30 (Zinc transporter), member 1.
      
 0.654
sod2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.613
slc30a1b
Solute carrier family 30 member 1b.
      
 0.603
znf142
Zinc finger protein 142.
    
 
 0.601
mtnr1c
Melatonin receptor type 1C; High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity); Belongs to the G-protein coupled receptor 1 family.
      
 0.574
slc30a4
Solute carrier family 30 (Zinc transporter), member 4.
   
  
 0.566
mtnr1al
Melatonin receptor type 1A-like; Belongs to the G-protein coupled receptor 1 family.
      
 0.562
atox1
Antioxidant 1 copper chaperone.
   
  
 0.554
sod1
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.
    
 
 0.551
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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