Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
tnfrsf19Tumor necrosis factor receptor superfamily, member 19. (356 aa)    
Predicted Functional Partners:
eda
Ectodysplasin A; Belongs to the tumor necrosis factor family.
    
 0.957
zbtb47a
Zinc finger and BTB domain-containing 47a.
      
 0.780
bcl9l
B-cell CLL/lymphoma 9-like protein; Transcriptional regulator that may act as an activator (By similarity). Plays a role for mesoderm patterning in early embryogenesis; Belongs to the BCL9 family.
      
 0.734
rell2
RELT-like 2.
     
  0.614
adgrg4a
Adhesion G protein-coupled receptor G4a; Belongs to the G-protein coupled receptor 2 family.
      
 0.599
marcksa
Myristoylated alanine-rich protein kinase C substrate a.
      
 0.594
dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40.
      
 0.589
cita
Citron rho-interacting serine/threonine kinase a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
      
 0.588
tnfrsf21
Tumor necrosis factor receptor superfamily, member 21.
      
 0.580
rtn4rl1b
Reticulon 4 receptor-like 1b.
      
 0.576
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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