STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trim54Tripartite motif-containing 54. (359 aa)    
Predicted Functional Partners:
uckl1a
Uridine-cytidine kinase; Belongs to the uridine kinase family.
    
 
 0.677
lims2
LIM domain-containing protein.
    
 
 0.673
ubr7
Ubiquitin protein ligase E3 component n-recognin 7.
      
 0.644
ttc13
Tetratricopeptide repeat domain 13.
    
 
 0.592
mybpc2b
Myosin-binding protein Cb.
    
 
 0.592
gas2l3
Growth arrest-specific 2-like 3.
    
 
 0.577
rnf217
RBR-type E3 ubiquitin transferase.
   
 
 0.575
reps1
RALBP1-associated Eps domain-containing 1.
   
  
 0.571
trim2b
Tripartite motif-containing 2b.
      
 0.568
rnf19b
E3 ubiquitin-protein ligase RNF19B; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells. Protects against staurosporin-induced cell death.
   
 
 0.547
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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