Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
usp39Ubiquitin-specific peptidase 39. (497 aa)    
Predicted Functional Partners:
prpf8
Pre-mRNA-processing factor 8.
   
 
 0.984
eftud2
Elongation factor Tu GTP-binding domain-containing 2.
   
 
 0.973
snrnp40
Small nuclear ribonucleoprotein 40 (U5).
   
 
 0.953
cd2bp2
CD2 (cytoplasmic tail)-binding protein 2.
    
   0.943
sart1
Spliceosome-associated factor 1, recruiter of U4/U6.U5 tri-snRNP.
   
 
 0.924
ddx23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.
   
 0.923
prpf31
U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.
   
 
 0.916
snrpa1
Small nuclear ribonucleoprotein polypeptide A.
   
 
 0.899
snrnp27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein; May play a role in mRNA splicing.
   
 
 0.895
lsm4
U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
    
 
 0.887
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (18%) [HD]