Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cxcr4bChemokine (C-X-C motif), receptor 4b; Belongs to the G-protein coupled receptor 1 family. (353 aa)    
Predicted Functional Partners:
cxcl12a
Chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family.
   
 0.999
cxcl12b
Chemokine (C-X-C motif) ligand 12B (Stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family.
   
 0.996
arrb1
Arrestin, beta 1.
    
 0.966
cxcr4a
Chemokine (C-X-C motif) receptor 4a; Belongs to the G-protein coupled receptor 1 family.
     
  0.950
arrb2b
Arrestin, beta 2b.
    
 0.945
arrb2a
Arrestin, beta 2a.
    
 0.945
cxcl14
Chemokine (C-X-C motif) ligand 14.
    
 0.939
ackr3b
Atypical chemokine receptor 3b; Belongs to the G-protein coupled receptor 1 family.
    
0.938
ackr3a
Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family.
    
0.932
gna12a
Guanine nucleotide-binding protein (G protein) alpha 12a.
    
 0.914
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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