Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ltkTyrosine-protein kinase receptor. (1530 aa)    
Predicted Functional Partners:
EML4
EMAP like 4.
   
 0.942
grb2b
Growth factor receptor-bound protein 2b.
    
 0.921
alkal1
ALK and LTK ligand 1.
    
 0.917
grb2a
Growth factor receptor-bound protein 2a.
    
 0.904
alkal2b
ALK and LTK ligand 2b.
    
 0.861
alkal2a
ALK and LTK ligand 2a.
    
 
 0.814
egfra
Epidermal growth factor receptor precursor.
    
 0.796
pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.793
pik3ca
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.788
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 0.783
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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