node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
col11a1b | prrx1b | ENSDARP00000049588 | ENSDARP00000061587 | Collagen, type XI, alpha 1b. | Paired-related homeobox 1b. | 0.495 |
foxc1a | prrx1b | ENSDARP00000105372 | ENSDARP00000061587 | Forkhead box C1-A; DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA bending. Required for cell viability and resistance to oxidative stress in the eye. Promotes cell growth inhibition by stopping the cell cycle in the G1 phase through TGFB1- mediated signals. Involved in epithelia [...] | Paired-related homeobox 1b. | 0.518 |
he1.3 | mak | ENSDARP00000118735 | ENSDARP00000076797 | Metalloendopeptidase. | Male germ cell-associated kinase. | 0.406 |
he1.3 | prrx1b | ENSDARP00000118735 | ENSDARP00000061587 | Metalloendopeptidase. | Paired-related homeobox 1b. | 0.625 |
hhex | meis1a | ENSDARP00000137249 | ENSDARP00000026780 | Hematopoietically-expressed homeobox protein hhex; Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. Regulates the differentiation of both endothelial and blood cells. Plays a role in embryonic dorsoventral patterning by regulating bmp expression. May establish anterior identity. Functions in the embryo to regulate liver development. Functions extraembryonically to generate organ chirality. | Myeloid ecotropic viral integration site 4.1a. | 0.465 |
hhex | meis2b | ENSDARP00000137249 | ENSDARP00000034815 | Hematopoietically-expressed homeobox protein hhex; Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. Regulates the differentiation of both endothelial and blood cells. Plays a role in embryonic dorsoventral patterning by regulating bmp expression. May establish anterior identity. Functions in the embryo to regulate liver development. Functions extraembryonically to generate organ chirality. | Myeloid ecotropic viral integration site 2.1. | 0.471 |
hhex | prrx1b | ENSDARP00000137249 | ENSDARP00000061587 | Hematopoietically-expressed homeobox protein hhex; Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. Regulates the differentiation of both endothelial and blood cells. Plays a role in embryonic dorsoventral patterning by regulating bmp expression. May establish anterior identity. Functions in the embryo to regulate liver development. Functions extraembryonically to generate organ chirality. | Paired-related homeobox 1b. | 0.461 |
mak | he1.3 | ENSDARP00000076797 | ENSDARP00000118735 | Male germ cell-associated kinase. | Metalloendopeptidase. | 0.406 |
mak | prrx1b | ENSDARP00000076797 | ENSDARP00000061587 | Male germ cell-associated kinase. | Paired-related homeobox 1b. | 0.444 |
meis1a | hhex | ENSDARP00000026780 | ENSDARP00000137249 | Myeloid ecotropic viral integration site 4.1a. | Hematopoietically-expressed homeobox protein hhex; Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. Regulates the differentiation of both endothelial and blood cells. Plays a role in embryonic dorsoventral patterning by regulating bmp expression. May establish anterior identity. Functions in the embryo to regulate liver development. Functions extraembryonically to generate organ chirality. | 0.465 |
meis1a | prrx1b | ENSDARP00000026780 | ENSDARP00000061587 | Myeloid ecotropic viral integration site 4.1a. | Paired-related homeobox 1b. | 0.456 |
meis2b | hhex | ENSDARP00000034815 | ENSDARP00000137249 | Myeloid ecotropic viral integration site 2.1. | Hematopoietically-expressed homeobox protein hhex; Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. Regulates the differentiation of both endothelial and blood cells. Plays a role in embryonic dorsoventral patterning by regulating bmp expression. May establish anterior identity. Functions in the embryo to regulate liver development. Functions extraembryonically to generate organ chirality. | 0.471 |
meis2b | prrx1b | ENSDARP00000034815 | ENSDARP00000061587 | Myeloid ecotropic viral integration site 2.1. | Paired-related homeobox 1b. | 0.437 |
polr1b | prrx1b | ENSDARP00000100185 | ENSDARP00000061587 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Paired-related homeobox 1b. | 0.498 |
prrx1b | col11a1b | ENSDARP00000061587 | ENSDARP00000049588 | Paired-related homeobox 1b. | Collagen, type XI, alpha 1b. | 0.495 |
prrx1b | foxc1a | ENSDARP00000061587 | ENSDARP00000105372 | Paired-related homeobox 1b. | Forkhead box C1-A; DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA bending. Required for cell viability and resistance to oxidative stress in the eye. Promotes cell growth inhibition by stopping the cell cycle in the G1 phase through TGFB1- mediated signals. Involved in epithelia [...] | 0.518 |
prrx1b | he1.3 | ENSDARP00000061587 | ENSDARP00000118735 | Paired-related homeobox 1b. | Metalloendopeptidase. | 0.625 |
prrx1b | hhex | ENSDARP00000061587 | ENSDARP00000137249 | Paired-related homeobox 1b. | Hematopoietically-expressed homeobox protein hhex; Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. Regulates the differentiation of both endothelial and blood cells. Plays a role in embryonic dorsoventral patterning by regulating bmp expression. May establish anterior identity. Functions in the embryo to regulate liver development. Functions extraembryonically to generate organ chirality. | 0.461 |
prrx1b | mak | ENSDARP00000061587 | ENSDARP00000076797 | Paired-related homeobox 1b. | Male germ cell-associated kinase. | 0.444 |
prrx1b | meis1a | ENSDARP00000061587 | ENSDARP00000026780 | Paired-related homeobox 1b. | Myeloid ecotropic viral integration site 4.1a. | 0.456 |