Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rbbp5Retinoblastoma-binding protein 5. (512 aa)    
Predicted Functional Partners:
dpy30
Dpy-30 histone methyltransferase complex regulatory subunit.
   
 0.999
wdr5
WD repeat domain 5.
   
0.999
ash2l
Ash2-like, histone lysine methyltransferase complex subunit.
    
 0.999
men1
Multiple endocrine neoplasia I.
   
 0.998
ncoa6
Nuclear receptor coactivator 6.
    
 
 0.992
wdr82
WD repeat-containing protein 82; Component of a chromatin regulatory complex involved in regulating chromatin structure in the nucleus; Belongs to the WD repeat SWD2 family.
    
 0.991
kmt2d
Lysine (K)-specific methyltransferase 2D.
    
 0.987
cxxc1b
CXXC finger protein 1b.
    
 0.973
kmt2a
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
    
 0.973
kmt2ca
Lysine (K)-specific methyltransferase 2Ca.
    
 0.959
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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