STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ncs1bFrequenin homolog b (Drosophila). (190 aa)    
Predicted Functional Partners:
pi4kb
Phosphatidylinositol 4-kinase beta; Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP).
    
 
 0.934
syt7a
Synaptotagmin VIIa.
   
  
 0.744
syt7b
Synaptotagmin VIIb.
   
  
 0.737
mcf2la
Mcf.2 cell line-derived-transforming sequence-like a.
      
 0.582
calm2a
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
   
 
 0.578
drd2b
Dopamine D2c receptor; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.555
drd3
Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.554
drd2a
Dopamine D2a receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.554
ric8a
Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity).
   
 
 0.528
wdr90
WD repeat domain 90.
    
 
 0.492
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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