Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C8H5orf51UPF0600 protein C5orf51 homolog; Belongs to the UPF0600 family. (276 aa)    
Predicted Functional Partners:
rmc1
Regulator of MON1-CCZ1.
      
 0.701
ccz1
Vacuolar fusion protein CCZ1 homolog.
    
 
 0.649
wdr91
WD repeat-containing protein 91; Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport; Belongs to the WD repeat WDR91 family.
      
 0.628
rab7a
RAB7a, member RAS oncogene family.
    
 
 0.613
rab7b
RAB7b, member RAS oncogene family.
    
 
 0.613
zgc:100918
Zgc:100918.
    
 
 0.613
lrpprc
Leucine-rich pentatricopeptide repeat-containing.
      
 0.478
mon1bb
MON1 secretory-trafficking family member Bb.
      
 0.472
mon1a
MON1 secretory-trafficking family member A.
      
 0.472
mon1ba
MON1 secretory-trafficking family member Ba.
      
 0.472
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.