node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ap4b1 | ap4e1 | ENSDARP00000014260 | ENSDARP00000138623 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. | 0.999 |
ap4b1 | ap4m1 | ENSDARP00000014260 | ENSDARP00000073893 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | 0.999 |
ap4b1 | ap4s1 | ENSDARP00000014260 | ENSDARP00000061852 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | 0.999 |
ap4b1 | ap5z1 | ENSDARP00000014260 | ENSDARP00000128237 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | Adaptor-related protein complex 5 subunit zeta 1. | 0.821 |
ap4b1 | ddhd1b | ENSDARP00000014260 | ENSDARP00000053840 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | DDHD domain-containing 1b. | 0.734 |
ap4b1 | fa2h | ENSDARP00000014260 | ENSDARP00000107067 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.650 |
ap4b1 | spg7 | ENSDARP00000014260 | ENSDARP00000089209 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | SPG7 matrix AAA peptidase subunit, paraplegin. | 0.729 |
ap4b1 | tecpr2 | ENSDARP00000014260 | ENSDARP00000121461 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | Tectonin beta-propeller repeat-containing 2. | 0.660 |
ap4b1 | tepsin | ENSDARP00000014260 | ENSDARP00000096307 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | TEPSIN adaptor-related protein complex 4 accessory protein. | 0.787 |
ap4b1 | vps37a | ENSDARP00000014260 | ENSDARP00000073136 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | Vacuolar protein sorting 37A. | 0.739 |
ap4e1 | ap4b1 | ENSDARP00000138623 | ENSDARP00000014260 | AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | 0.999 |
ap4e1 | ap4m1 | ENSDARP00000138623 | ENSDARP00000073893 | AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | 0.997 |
ap4e1 | ap4s1 | ENSDARP00000138623 | ENSDARP00000061852 | AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | 0.999 |
ap4e1 | ap5z1 | ENSDARP00000138623 | ENSDARP00000128237 | AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. | Adaptor-related protein complex 5 subunit zeta 1. | 0.817 |
ap4e1 | ddhd1b | ENSDARP00000138623 | ENSDARP00000053840 | AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. | DDHD domain-containing 1b. | 0.636 |
ap4e1 | fa2h | ENSDARP00000138623 | ENSDARP00000107067 | AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.520 |
ap4e1 | spg7 | ENSDARP00000138623 | ENSDARP00000089209 | AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. | SPG7 matrix AAA peptidase subunit, paraplegin. | 0.725 |
ap4e1 | tecpr2 | ENSDARP00000138623 | ENSDARP00000121461 | AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. | Tectonin beta-propeller repeat-containing 2. | 0.621 |
ap4e1 | tepsin | ENSDARP00000138623 | ENSDARP00000096307 | AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. | TEPSIN adaptor-related protein complex 4 accessory protein. | 0.790 |
ap4e1 | vps37a | ENSDARP00000138623 | ENSDARP00000073136 | AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. | Vacuolar protein sorting 37A. | 0.669 |