| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SHLD2 | mad2l2 | ENSDARP00000117245 | ENSDARP00000062253 | Si:ch211-134m17.9. | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | 0.961 |
| SHLD2 | rev3l | ENSDARP00000117245 | ENSDARP00000086696 | Si:ch211-134m17.9. | REV3-like, DNA directed polymerase zeta catalytic subunit. | 0.476 |
| SHLD2 | zgc:101664 | ENSDARP00000117245 | ENSDARP00000051776 | Si:ch211-134m17.9. | Zgc:101664. | 0.938 |
| fzr1a | mad2l1 | ENSDARP00000003004 | ENSDARP00000003616 | Fizzy/cell division cycle 20 related 1 (Drosophila). | MAD2 mitotic arrest deficient-like 1 (yeast). | 0.978 |
| fzr1a | mad2l2 | ENSDARP00000003004 | ENSDARP00000062253 | Fizzy/cell division cycle 20 related 1 (Drosophila). | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | 0.945 |
| mad2l1 | fzr1a | ENSDARP00000003616 | ENSDARP00000003004 | MAD2 mitotic arrest deficient-like 1 (yeast). | Fizzy/cell division cycle 20 related 1 (Drosophila). | 0.978 |
| mad2l1 | mad2l2 | ENSDARP00000003616 | ENSDARP00000062253 | MAD2 mitotic arrest deficient-like 1 (yeast). | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | 0.962 |
| mad2l1 | pold1 | ENSDARP00000003616 | ENSDARP00000055858 | MAD2 mitotic arrest deficient-like 1 (yeast). | DNA polymerase. | 0.474 |
| mad2l1 | rev3l | ENSDARP00000003616 | ENSDARP00000086696 | MAD2 mitotic arrest deficient-like 1 (yeast). | REV3-like, DNA directed polymerase zeta catalytic subunit. | 0.447 |
| mad2l2 | SHLD2 | ENSDARP00000062253 | ENSDARP00000117245 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | Si:ch211-134m17.9. | 0.961 |
| mad2l2 | fzr1a | ENSDARP00000062253 | ENSDARP00000003004 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | Fizzy/cell division cycle 20 related 1 (Drosophila). | 0.945 |
| mad2l2 | mad2l1 | ENSDARP00000062253 | ENSDARP00000003616 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | MAD2 mitotic arrest deficient-like 1 (yeast). | 0.962 |
| mad2l2 | pold1 | ENSDARP00000062253 | ENSDARP00000055858 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | DNA polymerase. | 0.946 |
| mad2l2 | pold2 | ENSDARP00000062253 | ENSDARP00000122064 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | Polymerase (DNA directed), delta 2, regulatory subunit. | 0.981 |
| mad2l2 | pold3 | ENSDARP00000062253 | ENSDARP00000092475 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | Polymerase (DNA-directed), delta 3, accessory subunit. | 0.981 |
| mad2l2 | pole | ENSDARP00000062253 | ENSDARP00000075852 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.941 |
| mad2l2 | rev1 | ENSDARP00000062253 | ENSDARP00000115859 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | 0.998 |
| mad2l2 | rev3l | ENSDARP00000062253 | ENSDARP00000086696 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | REV3-like, DNA directed polymerase zeta catalytic subunit. | 0.999 |
| mad2l2 | zgc:101664 | ENSDARP00000062253 | ENSDARP00000051776 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the [...] | Zgc:101664. | 0.956 |
| pold1 | mad2l1 | ENSDARP00000055858 | ENSDARP00000003616 | DNA polymerase. | MAD2 mitotic arrest deficient-like 1 (yeast). | 0.474 |
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