Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thap12aTHAP domain-containing 12a. (748 aa)    
Predicted Functional Partners:
dnajc3a
DnaJ (Hsp40) homolog, subfamily C, member 3a.
    
 
 0.741
pkz
Protein kinase-containing Z-DNA-binding domains.
    
 
 0.631
thap7
THAP domain-containing 7.
    
 
 0.617
dnajc3b
DnaJ (Hsp40) homolog, subfamily C, member 3b.
    
 
 0.610
thap4
THAP domain-containing 4.
      
 0.607
prkra
Interferon-inducible double-stranded RNA-dependent protein kinase activator A homolog; Activates eif2ak2/pkr in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of eif2s1/efi2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by dicer1 and for subsequent siRNA-mediated post- transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by dicer1 (By similarity).
      
 0.600
ifnphi4
Interferon phi 4.
      
 0.561
ifrd1
Interferon-related developmental regulator 1.
      
 0.559
thap3
THAP domain-containing, apoptosis-associated protein 3.
      
 0.546
tacc1
Transforming, acidic coiled-coil-containing protein 1.
    
   0.543
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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