Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
slc38a5aSolute carrier family 38 member 5a. (500 aa)    
Predicted Functional Partners:
f2rl1.2
Coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2.
      
 0.736
slc2a12
Solute carrier family 2, facilitated glucose transporter member 12; Insulin-regulated facilitative glucose transporter.
   
 
 0.617
fam110b
Protein FAM110B.
      
 0.573
tmem106bb
Transmembrane protein 106B; Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking; Belongs to the TMEM106 family.
      
 0.556
slc17a8
Vesicular glutamate transporter 3; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
     
 0.513
adck5
AarF domain-containing kinase 5.
      
 0.502
lamtor2
Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity).
    
 0.485
nceh1a
Neutral cholesterol ester hydrolase 1a.
   
  
 0.464
lamtor5
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5.
    
 0.461
gcgra
Glucagon receptor a; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.452
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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