Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
parp6aPoly (ADP-ribose) polymerase family, member 6a. (196 aa)    
Predicted Functional Partners:
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
  
 
 0.909
ENSDARP00000148081
PARP catalytic domain-containing protein.
 
      0.900
rps3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
  
 
 0.764
rps15
Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
  
  0.756
rpl11
60S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
  
 
 0.749
rpl23
60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.723
gpia
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.722
gpib
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.722
pgk1
Phosphoglycerate kinase.
  
 0.721
mycbpap
Mycbp-associated protein.
  
 0.721
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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