ptpn1 protein (Danio rerio) - STRING interaction network

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Score

ptpn1

Protein tyrosine phosphatase non-receptor type 1. (350 aa)

Predicted Functional Partners:

insra

0.985

ctnnb1

0.974

irs1

0.972

insrb

0.961

A2BFQ2_DANRE

0.961

E7F0F4_DANRE

0.954

irs4a

0.954

ctnnb2

0.913

irs2a

0.895

irs2b

0.895

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A2BFQ2_DANRE	E7F0F4_DANRE	ENSDARP00000117614	ENSDARP00000003269	Si:ch211-284e13.4.	Si:ch73-335l21.1.	0.944
A2BFQ2_DANRE	insra	ENSDARP00000117614	ENSDARP00000023951	Si:ch211-284e13.4.	Tyrosine-protein kinase receptor.	0.942
A2BFQ2_DANRE	insrb	ENSDARP00000117614	ENSDARP00000096601	Si:ch211-284e13.4.	Tyrosine-protein kinase receptor.	0.942
A2BFQ2_DANRE	irs1	ENSDARP00000117614	ENSDARP00000070706	Si:ch211-284e13.4.	Insulin receptor substrate 1.	0.876
A2BFQ2_DANRE	irs2a	ENSDARP00000117614	ENSDARP00000053923	Si:ch211-284e13.4.	Insulin receptor substrate 2a.	0.650
A2BFQ2_DANRE	irs2b	ENSDARP00000117614	ENSDARP00000136042	Si:ch211-284e13.4.	Insulin receptor substrate 2b.	0.650
A2BFQ2_DANRE	irs4a	ENSDARP00000117614	ENSDARP00000110181	Si:ch211-284e13.4.	Insulin receptor substrate 4a.	0.818
A2BFQ2_DANRE	ptpn1	ENSDARP00000117614	ENSDARP00000062692	Si:ch211-284e13.4.	Protein tyrosine phosphatase non-receptor type 1.	0.961
E7F0F4_DANRE	A2BFQ2_DANRE	ENSDARP00000003269	ENSDARP00000117614	Si:ch73-335l21.1.	Si:ch211-284e13.4.	0.944
E7F0F4_DANRE	insra	ENSDARP00000003269	ENSDARP00000023951	Si:ch73-335l21.1.	Tyrosine-protein kinase receptor.	0.966
E7F0F4_DANRE	insrb	ENSDARP00000003269	ENSDARP00000096601	Si:ch73-335l21.1.	Tyrosine-protein kinase receptor.	0.949
E7F0F4_DANRE	irs1	ENSDARP00000003269	ENSDARP00000070706	Si:ch73-335l21.1.	Insulin receptor substrate 1.	0.917
E7F0F4_DANRE	irs2a	ENSDARP00000003269	ENSDARP00000053923	Si:ch73-335l21.1.	Insulin receptor substrate 2a.	0.809
E7F0F4_DANRE	irs2b	ENSDARP00000003269	ENSDARP00000136042	Si:ch73-335l21.1.	Insulin receptor substrate 2b.	0.809
E7F0F4_DANRE	irs4a	ENSDARP00000003269	ENSDARP00000110181	Si:ch73-335l21.1.	Insulin receptor substrate 4a.	0.819
E7F0F4_DANRE	ptpn1	ENSDARP00000003269	ENSDARP00000062692	Si:ch73-335l21.1.	Protein tyrosine phosphatase non-receptor type 1.	0.954
ctnnb1	ctnnb2	ENSDARP00000139205	ENSDARP00000076115	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...]	Catenin, beta 2.	0.986
ctnnb1	insra	ENSDARP00000139205	ENSDARP00000023951	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...]	Tyrosine-protein kinase receptor.	0.823
ctnnb1	insrb	ENSDARP00000139205	ENSDARP00000096601	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...]	Tyrosine-protein kinase receptor.	0.828
ctnnb1	irs1	ENSDARP00000139205	ENSDARP00000070706	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...]	Insulin receptor substrate 1.	0.447

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