Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ctnnb1 | ctnnb2 | ENSDARP00000139205 | ENSDARP00000076115 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Catenin, beta 2. | 0.924 |
| ctnnb1 | irs1 | ENSDARP00000139205 | ENSDARP00000070706 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Insulin receptor substrate 1. | 0.411 |
| ctnnb1 | ptpn1 | ENSDARP00000139205 | ENSDARP00000062692 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Protein tyrosine phosphatase non-receptor type 1. | 0.933 |
| ctnnb1 | src | ENSDARP00000139205 | ENSDARP00000093618 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Proto-oncogene tyrosine-protein kinase Src; Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy bet [...] | 0.981 |
| ctnnb2 | ctnnb1 | ENSDARP00000076115 | ENSDARP00000139205 | Catenin, beta 2. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.924 |
| ctnnb2 | ptpn1 | ENSDARP00000076115 | ENSDARP00000062692 | Catenin, beta 2. | Protein tyrosine phosphatase non-receptor type 1. | 0.914 |
| ctnnb2 | src | ENSDARP00000076115 | ENSDARP00000093618 | Catenin, beta 2. | Proto-oncogene tyrosine-protein kinase Src; Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy bet [...] | 0.909 |
| gipc1 | ptpn1 | ENSDARP00000134004 | ENSDARP00000062692 | Regulator of G-protein signaling 19-interacting protein 1. | Protein tyrosine phosphatase non-receptor type 1. | 0.747 |
| gipc1 | src | ENSDARP00000134004 | ENSDARP00000093618 | Regulator of G-protein signaling 19-interacting protein 1. | Proto-oncogene tyrosine-protein kinase Src; Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy bet [...] | 0.433 |
| insra | insrb | ENSDARP00000023951 | ENSDARP00000096601 | Tyrosine-protein kinase receptor. | Tyrosine-protein kinase receptor. | 0.915 |
| insra | irs1 | ENSDARP00000023951 | ENSDARP00000070706 | Tyrosine-protein kinase receptor. | Insulin receptor substrate 1. | 0.969 |
| insra | irs2a | ENSDARP00000023951 | ENSDARP00000053923 | Tyrosine-protein kinase receptor. | Insulin receptor substrate 2a. | 0.976 |
| insra | irs2b | ENSDARP00000023951 | ENSDARP00000136042 | Tyrosine-protein kinase receptor. | Insulin receptor substrate 2b. | 0.974 |
| insra | irs4a | ENSDARP00000023951 | ENSDARP00000110181 | Tyrosine-protein kinase receptor. | Insulin receptor substrate 4a. | 0.965 |
| insra | ptpn1 | ENSDARP00000023951 | ENSDARP00000062692 | Tyrosine-protein kinase receptor. | Protein tyrosine phosphatase non-receptor type 1. | 0.957 |
| insra | src | ENSDARP00000023951 | ENSDARP00000093618 | Tyrosine-protein kinase receptor. | Proto-oncogene tyrosine-protein kinase Src; Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy bet [...] | 0.463 |
| insrb | insra | ENSDARP00000096601 | ENSDARP00000023951 | Tyrosine-protein kinase receptor. | Tyrosine-protein kinase receptor. | 0.915 |
| insrb | irs1 | ENSDARP00000096601 | ENSDARP00000070706 | Tyrosine-protein kinase receptor. | Insulin receptor substrate 1. | 0.966 |
| insrb | irs2a | ENSDARP00000096601 | ENSDARP00000053923 | Tyrosine-protein kinase receptor. | Insulin receptor substrate 2a. | 0.968 |
| insrb | irs2b | ENSDARP00000096601 | ENSDARP00000136042 | Tyrosine-protein kinase receptor. | Insulin receptor substrate 2b. | 0.968 |
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