Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
grb7Growth factor receptor-bound protein 7. (531 aa)    
Predicted Functional Partners:
mtor
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.731
insra
Tyrosine-protein kinase receptor.
    
 0.680
stap2a
Signal transducing adaptor family member 2a.
      
 0.660
igf1ra
Tyrosine-protein kinase receptor.
    
  0.639
igf1rb
Tyrosine-protein kinase receptor.
    
  0.639
insrb
Tyrosine-protein kinase receptor.
    
  0.639
grb2b
Growth factor receptor-bound protein 2b.
    
 0.616
csk
Tyrosine-protein kinase.
   
 0.613
E7EZC1_DANRE
Si:ch211-168d1.3.
   
 
 0.586
stap2b
Signal transducing adaptor family member 2b.
      
 0.585
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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