STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
itpkaKinase; Belongs to the inositol phosphokinase (IPK) family. (448 aa)    
Predicted Functional Partners:
inpp5l
Inositol polyphosphate-5-phosphatase L.
     
 0.968
plcb3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.956
Plcb2
Phosphoinositide phospholipase C.
     
 0.956
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.955
plcg1
Phosphoinositide phospholipase C.
     
 0.954
minpp1a
Multiple inositol-polyphosphate phosphatase 1a; Belongs to the histidine acid phosphatase family.
     
  0.948
inpp5jb
Inositol polyphosphate-5-phosphatase Jb.
     
 0.948
itpkca
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
  0.948
itpkb
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
  0.948
inpp5ka
Inositol polyphosphate-5-phosphatase Ka.
     
 0.948
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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