Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
phlda2Pleckstrin homology-like domain family A member 2; Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity). (136 aa)    
Predicted Functional Partners:
slc22a18
Solute carrier family 22 member 18.
      
 0.925
tssc4
Protein TSSC4; Belongs to the TSSC4 family.
      
 0.813
nap1l4a
Nucleosome assembly protein 1-like 4a; Belongs to the nucleosome assembly protein (NAP) family.
      
 0.805
osbpl5
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.767
pcdh12
Protocadherin 12.
      
 0.754
kcnq1.1
Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.
      
 0.710
igf2b
Insulin-like growth factor 2b.
      
 0.686
mest
Mesoderm-specific transcript.
      
 0.605
nupr1a
Nuclear protein 1a.
      
 0.594
gem
GTP-binding protein overexpressed in skeletal muscle.
      
 0.571
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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