hsh2d protein (Danio rerio) - STRING interaction network

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[Homology]

Score

hsh2d

Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling. (365 aa)

Predicted Functional Partners:

stk11

0.803

ppp2r2cb

0.803

pard6a

0.803

ppp2r2d

0.803

pik3r1

0.720

pik3r2

0.693

cdc42l2

0.685

cdc42

0.685

igflr1

0.665

pik3cb

0.632

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cdc42	hsh2d	ENSDARP00000129339	ENSDARP00000062985	Cell division cycle 42.	Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling.	0.685
cdc42	pard6a	ENSDARP00000129339	ENSDARP00000091677	Cell division cycle 42.	Par-6 family cell polarity regulator alpha.	0.989
cdc42	pik3cb	ENSDARP00000129339	ENSDARP00000128403	Cell division cycle 42.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.945
cdc42	pik3r1	ENSDARP00000129339	ENSDARP00000056212	Cell division cycle 42.	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).	0.935
cdc42	pik3r2	ENSDARP00000129339	ENSDARP00000130009	Cell division cycle 42.	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	0.914
cdc42l2	hsh2d	ENSDARP00000123487	ENSDARP00000062985	Cell division cycle 42-like 2.	Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling.	0.685
cdc42l2	pard6a	ENSDARP00000123487	ENSDARP00000091677	Cell division cycle 42-like 2.	Par-6 family cell polarity regulator alpha.	0.991
cdc42l2	pik3cb	ENSDARP00000123487	ENSDARP00000128403	Cell division cycle 42-like 2.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.945
cdc42l2	pik3r1	ENSDARP00000123487	ENSDARP00000056212	Cell division cycle 42-like 2.	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).	0.959
cdc42l2	pik3r2	ENSDARP00000123487	ENSDARP00000130009	Cell division cycle 42-like 2.	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	0.916
hsh2d	cdc42	ENSDARP00000062985	ENSDARP00000129339	Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling.	Cell division cycle 42.	0.685
hsh2d	cdc42l2	ENSDARP00000062985	ENSDARP00000123487	Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling.	Cell division cycle 42-like 2.	0.685
hsh2d	igflr1	ENSDARP00000062985	ENSDARP00000111941	Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling.	IGF-like family receptor 1.	0.665
hsh2d	pard6a	ENSDARP00000062985	ENSDARP00000091677	Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling.	Par-6 family cell polarity regulator alpha.	0.803
hsh2d	pik3cb	ENSDARP00000062985	ENSDARP00000128403	Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.632
hsh2d	pik3r1	ENSDARP00000062985	ENSDARP00000056212	Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling.	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).	0.720
hsh2d	pik3r2	ENSDARP00000062985	ENSDARP00000130009	Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling.	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	0.693
hsh2d	ppp2r2cb	ENSDARP00000062985	ENSDARP00000084300	Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.803
hsh2d	ppp2r2d	ENSDARP00000062985	ENSDARP00000131296	Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform; B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also ma [...]	0.803
hsh2d	stk11	ENSDARP00000062985	ENSDARP00000067735	Hematopoietic SH2 domain-containing protein homolog; May be an adapter protein involved in tyrosine kinase signaling.	Serine/threonine kinase 11; Belongs to the protein kinase superfamily.	0.803

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