STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpr173Probable G-protein coupled receptor 173; Is a receptor for the SMIM20 derived peptides Phoenixin-14 and Phoenixin-20 (By similarity). It mediates the Phoenixin-14 and Phoenixin-20 augmentation of gonadotropin-releasing hormone (GNRH) signaling in the hypothalamus and pituitary gland (By similarity). In the ovary, it mediates the effects of Phoenixin-14 and Phoenixin-20 induced granulosa cell proliferation during follicular growth (By similarity). (387 aa)    
Predicted Functional Partners:
smim20
Small integral membrane protein 20.
      
 0.971
dcun1d3
DCN1-like protein.
      
 0.806
gpr146
G protein-coupled receptor 146.
      
 0.743
mvb12a
Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (By similarity).
      
 0.727
gpr25
G protein-coupled receptor 25; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.685
tmem30b
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
      
 0.587
P2RY14
Purinergic receptor P2Y14; Belongs to the G-protein coupled receptor 1 family.
      
 0.553
gnrh2
Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family.
      
 0.540
kiss1rb
KISS1 receptor b.
   
  
 0.535
LOC556363
G protein-coupled receptor 108.
      
 0.517
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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