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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hook1Protein Hook homolog 1; May function to promote vesicle trafficking and/or fusion. (715 aa)    
Predicted Functional Partners:
aktip
AKT-interacting protein; May function to promote vesicle trafficking and/or fusion. May also regulate apoptosis (By similarity).
   
 0.949
fam160a2
FTS and Hook-interacting protein homolog; May function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).
    
 0.900
bicd2
Bicaudal D homolog 2 (Drosophila).
    
 
 0.878
BICD2
BICD cargo adaptor 2.
    
 
 0.878
rab11fip3
Rab11 family-interacting protein 3.
      
 0.842
F1QVK9_DANRE
Si:dkeyp-20g2.3.
      
 0.834
tsga10
Testis-specific, 10.
    
 
 0.791
bicdl1
BICD family-like cargo adapter 1; Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth.
    
 
 0.773
lrguk
Leucine-rich repeats and guanylate kinase domain-containing.
    
 
 0.755
tsnaxip1
Translin-associated factor X-interacting protein 1.
    
 
 0.703
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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