STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnajc5aaDnaJ (Hsp40) homolog, subfamily C, member 5aa. (202 aa)    
Predicted Functional Partners:
rab3ab
RAB3A, member RAS oncogene family, b.
   
 
 0.944
syt1a
Synaptotagmin Ia.
   
 0.890
vamp2
Vesicle-associated membrane protein 2.
   
 0.864
hspa8
Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...]
 
 0.854
slc32a1
Solute carrier family 32 (GABA vesicular transporter), member 1.
   
 0.824
hspa8b
Si:dkey-4p15.3; Belongs to the heat shock protein 70 family.
 
 0.818
tfip11
Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
    
 
 0.772
wdr7
WD repeat domain 7.
    
 
 0.772
cdc5l
CDC5 cell division cycle 5-like (S. pombe).
   
 
 0.771
hsc70
Heat shock cognate 70; Belongs to the heat shock protein 70 family.
 
 0.764
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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