Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
dgcr2DiGeorge syndrome critical region gene 2. (536 aa)    
Predicted Functional Partners:
ess2
Ess-2-splicing factor homolog.
 
    
 0.954
ppm1f
Protein phosphatase, Mg2+/Mn2+-dependent, 1F.
      
 0.831
dgcr6
DiGeorge syndrome critical region gene 6-like.
   
  
 0.829
slc25a1b
Tricarboxylate transport protein B, mitochondrial; Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate (By similarity). Required for proper neuromuscular junction formation.
      
 0.808
crnkl1
Crooked neck pre-mRNA-splicing factor 1.
      
 0.773
SCARF2
Scavenger receptor class F member 2.
    
 0.761
ascc2
Activating signal cointegrator 1 complex subunit 2.
      
 0.737
trmt2a
tRNA methyltransferase 2 homolog A; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
      
 0.729
kansl2
KAT8 regulatory NSL complex subunit 2.
   
  
 0.721
tango2
Transport and golgi organization 2 homolog (Drosophila).
      
 0.719
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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