Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cyp2p8Cytochrome P450, family 2, subfamily J, polypeptide 23; Belongs to the cytochrome P450 family. (496 aa)    
Predicted Functional Partners:
cyp3a65
Cytochrome P450, family 3, subfamily A, polypeptide 65; Belongs to the cytochrome P450 family.
  
 
0.785
cyp3c4
Cytochrome P450, family 3, subfamily C, polypeptide 4; Belongs to the cytochrome P450 family.
  
0.729
cyp3c1
Cytochrome P450, family 3, subfamily c, polypeptide 1; Belongs to the cytochrome P450 family.
  
 
0.718
suox
Sulfite oxidase.
     
 0.717
cyp26c1
Cytochrome P450, family 26, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
  
  
 0.707
cyp3c3
Cytochrome P450, family 3, subfamily c, polypeptide 3; Belongs to the cytochrome P450 family.
  
0.703
ephx2
Epoxide hydrolase 2, cytoplasmic.
   
 0.666
slc38a11
Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. Belongs to the amino acid/polyamine transporter 2 family.
      
 0.666
srd5a2a
3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
     
 0.664
E9QGC1_DANRE
Si:dkey-17e16.9.
   
 0.645
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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