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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vmo1aVitelline membrane outer layer 1 homolog a. (203 aa)    
Predicted Functional Partners:
ces2b
Si:ch211-93f2.1; Belongs to the type-B carboxylesterase/lipase family.
   
 
 0.810
vtg7
Vitellogenin 7.
    
 
 0.673
B8JME6_DANRE
Si:ch1073-126c3.2.
      
 0.661
nots
Nothepsin; Belongs to the peptidase A1 family.
    
 
 0.631
vtg2
Vitellogenin 2.
    
 
 0.545
shbg
Sex hormone-binding globulin.
      
 0.542
serpina1
Serine (Or cysteine) proteinase inhibitor, clade A (Alpha-1 antiproteinase, antitrypsin), member 1; Belongs to the serpin family.
      
 0.540
ckma
Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.
      
 0.480
sema5bb
Semaphorin-5B.
      
 0.480
c4b
Complement 4B (Chido blood group).
      
 0.479
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.