STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
capn3bCalpain 3b; Belongs to the peptidase C2 family. (723 aa)    
Predicted Functional Partners:
utp25
Digestive organ expansion factor; Regulates the p53 pathway to control the expansion growth of digestive organs. Required for the expansion growth of intestine, liver and exocrine pancreas, but not endocrine pancreas. May not play a major role during the early stage of endodermal organogenesis.
      
 0.839
fbl
Fibrillarin.
      
 0.725
bhmt
Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity).
   
  
 0.646
fabp10a
Fatty acid-binding protein 10-A, liver basic; Binds hydrophobic ligands, such as cholate, in the cytoplasm. May be involved in intracellular lipid transport (By similarity). Binds one cholate per subunit.
      
 0.545
cast
Calpastatin.
   
 
 0.522
lrguk
Leucine-rich repeats and guanylate kinase domain-containing.
   
 
 0.486
wee1
Wee1-like protein kinase.
      
 0.479
lbr
Lamin B receptor.
      
 0.453
capns1a
Calpain, small subunit 1 a.
   
 
0.421
chek1
CHK1 checkpoint homolog (S. pombe); Belongs to the protein kinase superfamily.
   
  
 0.419
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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