Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
capn3bCalpain 3b; Belongs to the peptidase C2 family. (723 aa)    
Predicted Functional Partners:
utp25
Digestive organ expansion factor; Regulates the p53 pathway to control the expansion growth of digestive organs. Required for the expansion growth of intestine, liver and exocrine pancreas, but not endocrine pancreas. May not play a major role during the early stage of endodermal organogenesis.
      
 0.892
capns1a
Calpain, small subunit 1 a.
   
 
0.745
slc41a2a
Solute carrier family 41 member 2a.
      
 0.734
nat9
N-acetyltransferase 9 (GCN5-related, putative).
      
 0.720
cast
Calpastatin.
   
 0.681
cmn
Calymmin.
   
 
 0.603
fbl
Fibrillarin.
      
 0.597
scpp9
Secretory calcium-binding phosphoprotein 9.
      
 0.595
ndrg1b
N-myc downstream-regulated 1b.
   
  
 0.574
hspb11
Heat shock protein beta-11; Belongs to the small heat shock protein (HSP20) family.
      
 0.558
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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