Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
grpGastrin-releasing peptide. (153 aa)    
Predicted Functional Partners:
grpr
Gastrin-releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.
   
 0.996
nmbb
Similar to neuromedin B.
     
 0.983
nmbr
Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.973
nmba
Neuromedin Ba.
     
 0.918
spcs2
Probable signal peptidase complex subunit 2; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.
   
 
 0.913
spcs3
Signal peptidase complex subunit 3.
   
 
 0.884
spcs1
Signal peptidase complex subunit 1 homolog (S. cerevisiae).
   
 
 0.882
gcgb
Glucagon b.
     
 0.760
kti12
Protein KTI12 homolog; Belongs to the KTI12 family.
     
 0.740
aldh18a1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.731
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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