STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gtf3c6General transcription factor IIIC, polypeptide 6, alpha. (183 aa)    
Predicted Functional Partners:
gtf3c2
General transcription factor IIIC, polypeptide 2, beta.
     
  0.800
gtf3c5
General transcription factor IIIC, polypeptide 5.
   
 
  0.800
gtf3c3
General transcription factor IIIC, polypeptide 3.
     
  0.800
brf2
Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family.
   
 
  0.544
brf1a
BRF1 RNA polymerase III transcription initiation factor subunit a.
     
  0.540
brf1b
BRF1 RNA polymerase III transcription initiation factor subunit b.
     
  0.540
gtf3c4
General transcription factor IIIC, polypeptide 4.
     
  0.540
zgc:162472
Zgc:162472.
     
  0.540
ENSDARP00000132798
B-block_TFIIIC domain-containing protein.
     
  0.540
LOC100535454
Uncharacterized protein.
     
  0.540
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.