Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
obscnaObscurin, cytoskeletal calmodulin and titin-interacting RhoGEF a. (1992 aa)    
Predicted Functional Partners:
obscnb
Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b.
 
   
0.935
mybpc3
Myosin-binding protein C3.
     
0.695
neb
Nebulin.
   
 
 0.670
myl2b
Myosin, light polypeptide 2, regulatory, cardiac, slow.
    
 0.648
RYR2
Uncharacterized protein.
   
 
 0.596
ubxn11
UBX domain protein 11.
      
 0.579
pes
Pescadillo; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
 
 0.556
nckipsd
NCK-interacting protein with SH3 domain.
    
 
 0.553
actn2b
Actinin, alpha 2b.
    
 0.546
myh7
Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.529
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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