Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nck2bCytoplasmic protein. (380 aa)    
Predicted Functional Partners:
pak1
Non-specific serine/threonine protein kinase.
    
 0.970
pak2a
Non-specific serine/threonine protein kinase.
    
 0.962
pak7
P21 protein (Cdc42/Rac)-activated kinase 7.
    
 0.954
pak4
Non-specific serine/threonine protein kinase.
    
 0.952
pak2b
Non-specific serine/threonine protein kinase.
    
 0.940
LOC100536197
Non-specific serine/threonine protein kinase.
    
 0.923
lcp2a
Lymphocyte cytosolic protein 2a.
    
 0.912
nck1b
Cytoplasmic protein.
  
  
 
0.903
pak6b
Non-specific serine/threonine protein kinase.
    
 0.893
nck1a
NCK adaptor protein 1a.
     
  0.844
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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