STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cxadrCoxsackievirus and adenovirus receptor homolog; May function as a homophilic cell adhesion molecule and be essential for tight junction integrity. May also be involved in transepithelial migration of leukocytes through adhesive interactions with jaml. The interaction between both receptors may also mediate the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair (By similarity). (372 aa)    
Predicted Functional Partners:
scn2b
Voltage-gated sodium channel beta 2 subunit splice variant D.
   
 0.917
nudt8
Nudix (nucleoside diphosphate-linked moiety X)-type motif 8.
   
  
 0.745
pdxp
Pyridoxal (pyridoxine, vitamin B6) phosphatase; Belongs to the HAD-like hydrolase superfamily.
      
 0.669
fam174b
Membrane protein FAM174B; Essential for Golgi structural integrity. Belongs to the FAM174 family.
      
 0.645
epcam
Epithelial cell adhesion molecule.
   
  
 0.609
lnx2a
Ligand of numb-protein X 2a.
   
 
 0.601
f11r.2
F11 receptor, tandem duplicate 2.
   
  
 0.581
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity).
   
 
 0.572
bpnt1
Bisphosphate nucleotidase 1.
      
 0.565
rpl36a
60S ribosomal protein L36a.
      
 0.562
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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