| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISCU | abcb7 | ENSDARP00000051606 | ENSDARP00000085602 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | 0.870 |
| ISCU | alas2 | ENSDARP00000051606 | ENSDARP00000056419 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.528 |
| ISCU | bola1 | ENSDARP00000051606 | ENSDARP00000058384 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | BolA family member 1; Belongs to the BolA/IbaG family. | 0.855 |
| ISCU | fech | ENSDARP00000051606 | ENSDARP00000125028 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.868 |
| ISCU | fxn | ENSDARP00000051606 | ENSDARP00000115873 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Frataxin. | 0.998 |
| ISCU | glrx5 | ENSDARP00000051606 | ENSDARP00000064111 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Glutaredoxin-related protein 5, mitochondrial; Monothiol glutaredoxin involved in iron-sulfur biogenesis. Required for normal iron homeostasis. Required for normal hemoglobin biosynthesis. | 0.883 |
| ISCU | iba57 | ENSDARP00000051606 | ENSDARP00000055617 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Putative transferase CAF17 homolog, mitochondrial; Required for normal heme biosynthesis. | 0.883 |
| ISCU | isca1 | ENSDARP00000051606 | ENSDARP00000068166 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. Belongs to the HesB/IscA family. | 0.968 |
| ISCU | isca2 | ENSDARP00000051606 | ENSDARP00000055610 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Iron-sulfur cluster assembly 2. | 0.965 |
| ISCU | nfs1 | ENSDARP00000051606 | ENSDARP00000084180 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | NFS1 nitrogen fixation 1 (S. cerevisiae). | 0.999 |
| abcb7 | ISCU | ENSDARP00000085602 | ENSDARP00000051606 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.870 |
| abcb7 | alas2 | ENSDARP00000085602 | ENSDARP00000056419 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | 5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.869 |
| abcb7 | bola1 | ENSDARP00000085602 | ENSDARP00000058384 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | BolA family member 1; Belongs to the BolA/IbaG family. | 0.503 |
| abcb7 | fech | ENSDARP00000085602 | ENSDARP00000125028 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.958 |
| abcb7 | fxn | ENSDARP00000085602 | ENSDARP00000115873 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Frataxin. | 0.948 |
| abcb7 | glrx5 | ENSDARP00000085602 | ENSDARP00000064111 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Glutaredoxin-related protein 5, mitochondrial; Monothiol glutaredoxin involved in iron-sulfur biogenesis. Required for normal iron homeostasis. Required for normal hemoglobin biosynthesis. | 0.960 |
| abcb7 | iba57 | ENSDARP00000085602 | ENSDARP00000055617 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Putative transferase CAF17 homolog, mitochondrial; Required for normal heme biosynthesis. | 0.890 |
| abcb7 | isca1 | ENSDARP00000085602 | ENSDARP00000068166 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. Belongs to the HesB/IscA family. | 0.910 |
| abcb7 | isca2 | ENSDARP00000085602 | ENSDARP00000055610 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Iron-sulfur cluster assembly 2. | 0.860 |
| abcb7 | nfs1 | ENSDARP00000085602 | ENSDARP00000084180 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | NFS1 nitrogen fixation 1 (S. cerevisiae). | 0.950 |