| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C20H20H6orf58 | acot17 | ENSDARP00000064418 | ENSDARP00000066942 | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | Acyl-CoA thioesterase 17. | 0.746 |
| C20H20H6orf58 | bhmt | ENSDARP00000064418 | ENSDARP00000040421 | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). | 0.585 |
| C20H20H6orf58 | birc5a | ENSDARP00000064418 | ENSDARP00000101794 | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | Baculoviral IAP repeat-containing 5a. | 0.717 |
| C20H20H6orf58 | bms1 | ENSDARP00000064418 | ENSDARP00000053760 | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | BMS1 ribosome biogenesis factor. | 0.670 |
| C20H20H6orf58 | f13a1a.1 | ENSDARP00000064418 | ENSDARP00000120334 | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | Coagulation factor XIII, A1 polypeptide a, tandem duplicate 1. | 0.570 |
| C20H20H6orf58 | fabp10a | ENSDARP00000064418 | ENSDARP00000056094 | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | Fatty acid-binding protein 10-A, liver basic; Binds hydrophobic ligands, such as cholate, in the cytoplasm. May be involved in intracellular lipid transport (By similarity). Binds one cholate per subunit. | 0.567 |
| C20H20H6orf58 | phc2a | ENSDARP00000064418 | ENSDARP00000054361 | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | Polyhomeotic-like protein 2; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity). | 0.564 |
| C20H20H6orf58 | soga3 | ENSDARP00000064418 | ENSDARP00000129239 | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | SOGA family member 3a. | 0.846 |
| C20H20H6orf58 | supv3l1 | ENSDARP00000064418 | ENSDARP00000099447 | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | ATP-dependent RNA helicase SUPV3L1, mitochondrial; Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation o [...] | 0.644 |
| C20H20H6orf58 | zfyve9a | ENSDARP00000064418 | ENSDARP00000131596 | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | Zinc finger, FYVE domain-containing 9a. | 0.566 |
| acot17 | C20H20H6orf58 | ENSDARP00000066942 | ENSDARP00000064418 | Acyl-CoA thioesterase 17. | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | 0.746 |
| acot17 | bhmt | ENSDARP00000066942 | ENSDARP00000040421 | Acyl-CoA thioesterase 17. | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). | 0.584 |
| bhmt | C20H20H6orf58 | ENSDARP00000040421 | ENSDARP00000064418 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | 0.585 |
| bhmt | acot17 | ENSDARP00000040421 | ENSDARP00000066942 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). | Acyl-CoA thioesterase 17. | 0.584 |
| bhmt | fabp10a | ENSDARP00000040421 | ENSDARP00000056094 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). | Fatty acid-binding protein 10-A, liver basic; Binds hydrophobic ligands, such as cholate, in the cytoplasm. May be involved in intracellular lipid transport (By similarity). Binds one cholate per subunit. | 0.745 |
| birc5a | C20H20H6orf58 | ENSDARP00000101794 | ENSDARP00000064418 | Baculoviral IAP repeat-containing 5a. | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | 0.717 |
| bms1 | C20H20H6orf58 | ENSDARP00000053760 | ENSDARP00000064418 | BMS1 ribosome biogenesis factor. | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | 0.670 |
| bms1 | supv3l1 | ENSDARP00000053760 | ENSDARP00000099447 | BMS1 ribosome biogenesis factor. | ATP-dependent RNA helicase SUPV3L1, mitochondrial; Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation o [...] | 0.653 |
| bms1 | zfyve9a | ENSDARP00000053760 | ENSDARP00000131596 | BMS1 ribosome biogenesis factor. | Zinc finger, FYVE domain-containing 9a. | 0.541 |
| f13a1a.1 | C20H20H6orf58 | ENSDARP00000120334 | ENSDARP00000064418 | Coagulation factor XIII, A1 polypeptide a, tandem duplicate 1. | Protein leg1a; Important for early development of liver, exocrine pancreas and intestine, probably through cell cycle regulation. In liver, its function is partially redundant with leg1b function. | 0.570 |